Choosing an audio interface with MIDI ports comes down to more than just sound quality. The right model should match your inputs, your workflow, and the gear you already use.
In this roundup, we focus on practical options for solo recording, small bands, and home studios, with an eye on value, compatibility, and expansion.
Best 10 Audio Interface with Midi Ports Picks for 2026
MIDI-Ready Studio Hub
Focusrite Scarlett 4i4 4th Gen
- MIDI I/O plus 4-in/4-out connectivity
- Two mic preamps, two Hi-Z inputs, four line inputs
- 120dB dynamic range with Auto Gain and Clip Safe
Best For: Home producers who want a flexible USB-C interface with MIDI and multiple inputs
Simple 2-Channel Interface
- 2-in/2-out layout with two preamps
- Hardware monitoring for direct tracking
- 24-bit/192kHz support in a compact design
Best For: Users who want a simple desktop interface for solo recording
Value 4x4 MIDI Interface
- 4x4 USB interface with 1x MIDI I/O
- Four MIDAS-designed mic preamps
- 24-bit/192kHz resolution and metal chassis
Best For: Budget buyers needing multiple inputs and MIDI in one interface
Portable Starter Interface
PreSonus AudioBox 96 25th Anniversary
- MIDI I/O with 2 mic preamps and 2 instrument inputs
- Bus-powered USB 2.0 design for portability
- Up to 24-bit/96kHz plus bundled software
Best For: Beginners and portable recordists who want a compact MIDI-capable interface
MIDI-Ready Hybrid Interface
MOTU M4 4x4 USB-C Audio Interface
- MIDI I/O for connecting external gear
- 4-in/4-out USB-C recording and playback
- Hardware monitoring plus LCD level display
Best For: Home studios and podcasters who need MIDI I/O in a compact interface
Compact Starter Interface
Focusrite Scarlett 2i2 4th Gen USB-C Audio Interface
- 4th Gen mic pres with 120dB dynamic range
- Auto Gain, Clip Safe, and Air mode included
- Software bundle covers recording, mixing, and mastering
Best For: Beginners and singer-songwriters who want easy recording, not MIDI ports
Bus-Powered MIDI Interface
Mackie Onyx Producer 2X2 USB Audio Interface with MIDI
- MIDI I/O in a portable 2x2 interface
- Two Onyx preamps with 48V phantom power
- Bus-powered USB design with direct monitoring
Best For: Mobile musicians who want MIDI I/O and easy grab-and-go recording
Compact Singer-Songwriter Pick
Focusrite Scarlett Solo 4th Gen USB-C Audio Interface
- 120dB dynamic range with 24-bit/192kHz recording
- 1 XLR mic preamp and 1 Hi-Z instrument input
- Includes Pro Tools Intro+, Ableton Live Lite, and Cubase LE
Best For: Solo vocal and guitar recording at home
Budget Dual-Input Starter
M-AUDIO M-Track Duo USB Audio Interface
- Two combo XLR/Line/Instrument inputs with phantom power
- USB/direct switch supports zero-latency monitoring
- Includes MPC Beats software for recording
Best For: Beginners making podcasts, vocals, and simple music recordings
Creator Workflow Hub
MAONO P1 USB Audio Interface with 70dB Gain
- Up to 70dB gain for dynamic microphones
- Dual USB ports support computer and mobile use
- Loopback, auto-gain, and mute controls for streaming
Best For: Streamers and mobile creators needing flexible audio routing
MIDI-Ready Studio Hub – Focusrite Scarlett 4i4 4th Gen
If you want an audio interface with midi ports that also gives you plenty of analog I/O, the Scarlett 4i4 4th Gen is built to handle a growing home studio. It combines two mic preamps, two Hi-Z inputs, four line inputs, and MIDI I/O, so you can connect mics, guitars, synths, and drum machines without running out of connections.
Best For: Musicians who need a flexible USB-C interface with MIDI I/O, multiple line inputs, and strong all-around recording performance.
Pros:
- Includes MIDI In/Out alongside 4-in/4-out connectivity.
- Two Scarlett 4th Gen mic preamps, two Hi-Z inputs, and four line inputs support a wide range of gear.
- 120dB dynamic range and 24-bit/192kHz converters aim for studio-quality recording.
- Auto Gain, Clip Safe, and Air mode add useful recording tools.
Cons:
- More interface than a basic 2-channel setup if you only record one source at a time.
- Requires USB-C style connectivity and includes a power supply, which may be less minimal for ultra-portable use.
The 4i4 stands out when you need MIDI plus enough inputs to build a compact but capable studio. It offers a strong balance of features for recording, monitoring, and connecting external instruments.
Simple 2-Channel Interface – MOTU M2 USB-C
The MOTU M2 is a straightforward audio interface for users who want clean 2-in/2-out recording without extra complexity. It focuses on hardware monitoring, two preamps, and 24-bit/192kHz support, making it a practical choice for small desktop setups.
Best For: Solo musicians, podcasters, and small setups that want a simple USB-C interface with reliable 2-channel recording.
Pros:
- 2-in/2-out layout keeps setup simple.
- Two preamps and hardware monitoring support basic tracking needs.
- 24-bit/192kHz resolution offers high-quality recording capability.
- USB-C connectivity works across macOS, Windows, and iOS according to the notes.
Cons:
- No MIDI ports are listed, so it is not the right fit if you need an audio interface with midi ports.
- Only two channels, so it is less expandable than 4-input interfaces.
The M2 is best viewed as a clean, efficient recording interface rather than a feature-heavy studio hub. If your priority is sound quality and simplicity, it fits that role well.
Value 4×4 MIDI Interface – Behringer U-PHORIA UMC404HD
If your search for an audio interface with midi ports is centered on value and I/O count, the Behringer U-PHORIA UMC404HD is a strong fit. It offers 4 inputs, 4 outputs, and 1x MIDI I/O, along with MIDAS-designed mic preamps and 24-bit/192kHz recording.
Best For: Budget-conscious users who need a 4×4 USB interface with MIDI and multiple mic channels.
Pros:
- Includes 1x MIDI I/O plus 4 inputs and 4 outputs.
- Four MIDAS-designed mic preamps add flexibility for multi-mic recording.
- 24-bit/192kHz resolution supports detailed audio capture.
- Metal chassis gives it a rugged, road-ready feel.
Cons:
- Bulkier than smaller 2-channel interfaces.
- Windows compatibility is explicitly listed in the notes, so platform fit should be checked carefully.
The UMC404HD is appealing if you need MIDI and multiple inputs without moving up to a more expensive interface. Its feature set is especially practical for recording several sources at once.
Portable Starter Interface – PreSonus AudioBox 96 25th Anniversary
The PreSonus AudioBox 96 is a compact option if you want an audio interface with midi ports for a simple recording setup. It combines two Class-A mic preamps, two instrument inputs, MIDI I/O, and bus-powered USB 2.0 operation, which makes it easy to use at home or on the go.
Best For: Portable home recordists and beginners who want a small USB interface with MIDI I/O and bundled software.
Pros:
- Includes MIDI I/O along with two mic preamps and two instrument inputs.
- Bus-powered USB 2.0 design reduces cable clutter and improves portability.
- Studio-grade converters support up to 24-bit/96kHz recording.
- Comes with a large software bundle, including Studio One Artist and Ableton Live Lite.
Cons:
- Limited to 2 channels, so it is not ideal for bigger recording sessions.
- Max sample rate tops out at 96kHz, below some higher-end interfaces.
This is a practical starter interface for anyone who wants MIDI support without a complicated setup. It focuses on portability, easy monitoring, and good core recording features.
MIDI-Ready Hybrid Interface – MOTU M4 4×4 USB-C Audio Interface
If you want an audio interface with midi ports that also keeps recording, mixing, and podcasting simple, the MOTU M4 is a strong all-around choice. It offers 4-in/4-out USB-C connectivity, MIDI I/O, low-latency monitoring, and a front-panel LCD for quick level checks.
Best For: Home studios, podcasters, and musicians who want a compact interface with MIDI I/O and flexible USB-C connectivity.
Pros:
- Includes MIDI I/O for connecting compatible gear alongside audio recording.
- 4-in/4-out USB-C design supports recording, mixing, and podcasting.
- Hardware monitoring and LCD screen make basic setup and level control easier.
- Comes with 6+GB of free content and a 2-year warranty.
Cons:
- Only two microphone preamps, so larger mic setups will need something else.
- No built-in operating system included, so it relies on your existing Mac/PC/iOS setup.
Overall, the M4 stands out as a practical audio interface with midi ports if you need a streamlined desktop unit that covers both audio and MIDI duties. Its feature set is especially appealing for creators who value easy monitoring and a clean, compact layout.
Compact Starter Interface – Focusrite Scarlett 2i2 4th Gen USB-C Audio Interface
The Focusrite Scarlett 2i2 4th Gen is a simple, high-quality USB-C interface for users who do not need midi ports but want a polished recording experience. It adds 4th Gen mic pres, Auto Gain, Clip Safe, and Air mode, making it easy to get clean vocals and guitar recordings quickly.
Best For: Singer-songwriters, beginners, and small studios that want a 2-channel interface with easy gain control and modern recording tools.
Pros:
- 120dB dynamic range and the same converters used in Focusrite’s flagship interfaces.
- Auto Gain and Clip Safe help prevent bad levels during recording.
- Air mode adds presence and harmonic drive to vocals and guitars.
- Includes Pro Tools Intro+, Ableton Live Lite, Cubase LE, and Hitmaker Expansion.
Cons:
- No MIDI I/O, so it is not the best fit if you specifically need an audio interface with midi ports.
- Only 2 channels, which limits more complex recording setups.
For straightforward recording, the Scarlett 2i2 4th Gen is a polished option with helpful automation and strong included software. It is less suitable for MIDI-based rigs, but it remains a very capable compact interface for vocals and instruments.
Bus-Powered MIDI Interface – Mackie Onyx Producer 2X2 USB Audio Interface with MIDI
Mackie Audio Interface, Onyx Producer 2X2 USB Audio Interface with MIDI (Onyx Producer 2-2)
Check Price On AmazonIf you need an audio interface with midi ports in a portable 2×2 format, the Mackie Onyx Producer 2X2 is built for that job. It combines 24-bit/192kHz recording, two Onyx mic preamps, and MIDI I/O in a bus-powered design that is easy to take on the go.
Best For: Mobile musicians and small studio users who want MIDI I/O, bus-powered convenience, and simple direct monitoring.
Pros:
- Includes MIDI I/O along with 2 in x 2 out audio connectivity.
- Two boutique-quality Onyx mic preamps with 48V phantom power.
- Zero-latency direct monitoring with dedicated outputs and headphone output.
- Bus-powered USB 2.0 design makes it easy to use without a power adapter.
Cons:
- Limited to 2 channels, so it is not ideal for larger recording sessions.
- Supported software is listed for iOS and macOS, while the details note Windows as the operating system.
The Onyx Producer 2X2 is a solid pick if portability and MIDI integration matter more than channel count. Its bus-powered build and direct monitoring make it especially practical for lightweight recording setups.
Compact Singer-Songwriter Pick – Focusrite Scarlett Solo 4th Gen USB-C Audio Interface
If you want an audio interface with midi ports, note that the Scarlett Solo 4th Gen is not that kind of unit—it focuses on a simple 2-channel recording setup for vocals and guitar. For solo music making, it offers USB-C connectivity, a 24-bit/192kHz path, and Focusrite’s updated Air mode for a more present vocal or guitar sound.
Best For: Singer-songwriters and solo creators who need a clean, compact interface for recording mic and instrument at home.
Pros:
- 120dB dynamic range and 24-bit/192kHz conversion
- 1 XLR mic preamp plus 1 Hi-Z instrument input
- Improved Air mode adds presence and harmonic drive
- Includes Pro Tools Intro+, Ableton Live Lite, Cubase LE, and plugins
Cons:
- No MIDI ports for external keyboards or controllers
- Only 2 channels, so it is not built for larger multi-input setups
- Best suited to basic recording rather than expanded routing
Overall, this is a strong choice if your priority is straightforward vocal-and-guitar recording with polished sound and included software. It is less suitable if MIDI connectivity is a must-have.
Budget Dual-Input Starter – M-AUDIO M-Track Duo USB Audio Interface
If you are shopping for an audio interface with midi ports, the M-Track Duo is not the match—it does not list MIDI connectivity, but it does cover the essentials for recording, podcasting, streaming, and live monitoring. Its two combo XLR/Line/Instrument inputs, USB/direct monitoring switch, and 48kHz resolution make it a practical entry-level option.
Best For: Beginners who want a portable, no-frills interface for vocals, guitar, podcasts, and livestreams.
Pros:
- Two combo XLR/Line/Instrument inputs with phantom power
- USB/direct monitoring switch for zero-latency monitoring
- 48kHz audio resolution for basic recording needs
- Includes MPC Beats software for production workflows
Cons:
- No MIDI ports are listed
- 48kHz max sample rate is lower than higher-end options
- More basic feature set than creator-focused interfaces
As a starter interface, the M-Track Duo is useful when you need simple I/O and dependable monitoring without paying for extra features. If MIDI is essential, you will need a different model.
Creator Workflow Hub – MAONO P1 USB Audio Interface with 70dB Gain
If you are specifically looking for an audio interface with midi ports, the MAONO P1 is not positioned as a MIDI-capable model in the supplied details. What it does emphasize is flexible hybrid connectivity for computer, phone, and iPad use, plus creator-friendly tools like auto-gain, loopback, and ProStudio2 software for routing audio in streaming and recording setups.
Best For: Streamers, podcasters, and mobile creators who want flexible routing and high-gain mic support.
Pros:
- Up to 70dB gain for demanding dynamic microphones
- 24-bit/192kHz recording with -130dB EIN
- Dual USB ports for computer plus phone or iPad workflows
- Auto-gain, loopback, and independent mute controls
Cons:
- No MIDI ports are mentioned in the product details
- Software-heavy workflow may be more than some users need
- Designed more for creator routing than traditional multi-instrument expansion
For creators who care most about streaming flexibility and clean microphone gain, the P1 stands out with useful workflow features. It is less compelling if MIDI connectivity is a priority.
How We Picked the Best Audio Interface with Midi Ports
We prioritized interfaces that combine reliable audio performance with built-in MIDI connectivity, sensible I/O layouts, and broad compatibility across modern recording setups. We also considered preamp quality, driver stability, portability, and whether the unit makes sense for beginners or more advanced users.
Quick Comparison
When comparing an Audio Interface with Midi Ports, think first about how many sources you need to record at once. Two-input models are ideal for vocals, guitar, and podcasting, while 4×4 designs are better for keyboards, drum machines, and small ensembles. USB-C models usually offer easier plug-and-play convenience, but older USB designs can still be strong values if you do not need the latest connection standard.
Key Buying Factors for Audio Interface with Midi Ports
Inputs and Outputs
Check whether you need combo mic/line inputs, instrument inputs, line outputs for monitors, and headphone jacks with independent level control. If you use external synths or controllers, MIDI in/out can be just as important as audio I/O.
Audio Quality and Gain
Look for clean preamps, enough gain for dynamic microphones, and low-noise performance at higher settings. For users with quiet microphones or gain-hungry mics, preamp headroom matters more than spec-sheet marketing.
Latency and Driver Support
Stable drivers and low round-trip latency are essential if you record software instruments or monitor through effects. This is especially important for Windows users, but Mac users should still value dependable software support.
Build and Workflow
Front-panel meters, direct monitoring, and sturdy knobs make daily use easier. A good interface should feel simple to operate even when your session gets busy.
Who Should Buy Which Audio Interface with Midi Ports?
If you are a solo artist or songwriter, a compact 2-in/2-out model may be enough, especially if your MIDI needs are limited to one keyboard or controller. If you work with hardware synths, drum machines, or multi-source recording, a larger Audio Interface with Midi Ports and more line inputs will give you much more flexibility.
Beginners should favor straightforward controls and good bundled software, while experienced users may want better metering, more outputs, and stronger integration with external gear. The best choice is the one that fits your setup now and still leaves room to grow.
